Interleukin 28 receptor, alpha subunit is a subunit for the interleukin-28 receptor. IL28RA is its human gene. The protein encoded by this gene belongs to the class II cytokine receptor …

The interleukin 28 receptor consists of an interleukin-28R alpha chain (IL-28RA) and another receptor, the beta subunit of the Interleukin-10 receptor (IL-10R2). [7] . IL-10R2 is part of the …

Interleukin (IL) 28 receptor α (IL28RA) is a well-known candidate for psoriasis susceptibility based on previous genome-wide association study (GWAS) analysis. However, the function of …

IL28RA, as a specific receptor for IFN-λ, plays a pivotal role in immune regulation across various diseases upon binding with IFN-λ. Our previous studies have noted an upregulation of IL28RA …

Feb 8, 2025 · Downregulated expression of IL28RA is involved in the pathogenesis of pancreatic ductal adenocarcinoma. Interferon III-related IL28RA variant is associated with rheumatoid …

We demonstrate the protective effects of the siRNA-mediated inhibition of the interleukin-28 receptor alpha (IL28RA) subunit on cardiomyocytes in hypoxia/reoxygenation (H/R) injury and …

IFNLR1 (interferon lambda receptor 1, also known as IL28RA) may have an essential role in anti-viral activity and immune regulation, and it has been recently reported that it inhibits...

Dec 20, 2024 · Interleukin 28A (IL28A) and interleukin 28B (IL28B) may play a role in immune regulation post-AMI by specifically binding to interleukin 28 receptor alpha (IL28RA). However, …

IFN-lambda1, -lambda2, and -lambda3 bind to the same receptor (known as IL28RA) to exert their antiviral, antitumor and immunomodulatory effects. Here, we identified IL28RA genes from the …

Apr 1, 2012 · IL28RA codes for a transmembrane protein that heterodimerizes with another subunit, IL-10RB, to form a type II cytokine receptor, which binds IL-28A, IL-28B and IL-29, …