Interleukin 21 receptor is a type I cytokine receptor. IL21R is its human gene. [5] The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21).

IL-21 produced by follicular helper CD4 T cells (T FH) acts directly on B cells via their IL-21 receptors (IL21R) to generate high-affinity, class-switched antibodies [1, 2].

Mar 30, 2025 · IL21R (Interleukin 21 Receptor) is a Protein Coding gene. Diseases associated with IL21R include Immunodeficiency 56 and Cryptosporidiosis-Chronic Cholangitis-Liver …

IL-21 (or IL-21R) knock-out mice infected with chronic LCMV (lymphocytic choriomeningitis virus) were not able to overcome chronic infection compared to normal mice.

Its private receptor, IL-21R, has been shown to activate the Janus kinase/signal transducers and activators of transcription signaling pathway upon ligand binding. Initial studies have …

We demonstrate that IL-21/IL-21R interactions play a critical role in allergic skin inflammation to e.c. introduced antigen by promoting the migration of skin DCs to DLNs and the subsequent …

Dec 9, 2024 · Title: IL21R hypomethylation as a biomarker for distinguishing benign and malignant breast tumours. Interleukin-21 receptor signaling promotes metabolic dysfunction …

Apr 22, 2014 · Interleukin-21 (IL-21) binding stabilizes the complex between the IL-21 receptor (IL-21R) and the common cytokine-γ chain, γ c, leading to the activation of Janus kinase 1...

Feb 8, 2025 · parathyroid hormone (PTH) and interleukin 21 receptor (IL21R), achieved consistent association results for bone mineral density in both discovery and replication …

Mar 5, 2024 · Clinical resource with information about IL21R, A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci., …