IL-10 Deficiency Accelerates Type 1 Diabetes Development
Il-10 deficiency in BDC2.5 + NOD mice promoted the generation of neutrophils in the bone marrow and increased the proportions of neutrophils in the periphery (blood, spleen, and …
IL-10 Deficiency Accelerates Type 1 Diabetes Development
Jul 30, 2021 · In this study, we investigated the role of interleukin 10 (IL-10) in the inhibition of diabetes in BDC2.5+ NOD mice by generating Il-10 -deficient BDC2.5+ NOD mice (BDC2.5+Il …
Interleukin-10 paradox: A potent immunoregulatory cytokine that has ...
To our knowledge, there are currently, no ongoing clinical trials focusing on IL-10 in T1D. Taken together, these findings indicate a complex role for IL-10 in autoimmune diabetes that is …
Altered Tim-1 and IL-10 Expression in Regulatory B Cell Subsets in …
Our study showed altered Tim-1 and IL-10 expression in regulatory B cell in T1D patients. Tim-1, as suggested by the present study, is associated with islet function and blood glucose levels. …
Clinical importance of cytokine (IL-6, IL-8, and IL-10) and
Oct 16, 2024 · It has been shown that proinflammatory cytokines released during the disease can exacerbate the condition, while anti-inflammatory cytokines offer protection. This study …
Altered Regulatory B Cell Subsets in Children with Type 1 Diabetes ...
Jul 21, 2020 · In the present study, we employed a flow cytometry approach to characterize different IL10-producing Breg subsets in the peripheral blood of T1D children and healthy …
Altered Tim-1 and IL-10 Expression in Regulatory B Cell ... - PubMed
Dec 21, 2021 · Our study showed altered Tim-1 and IL-10 expression in regulatory B cell in T1D patients. Tim-1, as suggested by the present study, is associated with islet function and blood …
Clinical importance of cytokine (IL-6, IL-8, and IL-10) and ... - Nature
Oct 16, 2024 · Type-1 diabetes (T1D) is an autoimmune disorder characterized by impaired insulin release by islet β cells. It has been shown that proinflammatory cytokines released …
Cytokines in type 1 diabetes: mechanisms of action and ...
Mar 16, 2020 · Cytokines that can induce regulatory functions—for example, IL-10, TGF-β and IL-33—are thought to restore immune tolerance and prevent β-cell damage. By contrast, …
Altered Tim-1 and IL-10 Expression in Regulatory B Cell Subsets in …
Our study showed altered Tim-1 and IL-10 expression in regulatory B cell in T1D patients. Tim-1, as suggested by the present study, is associated with islet function and blood glucose levels. …
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