IL-22 takes effect on non-hematopoietic cells – mainly stromal and epithelial cells. Effects involve stimulation of cell survival, proliferation and synthesis of antimicrobials including S100, Reg3β, Reg3γ and defensins. IL-22 thus participates in both wound healing and in …

The Ilyushin Il-22, USAF/DOD designation Type 10, [1] was the first Soviet jet-engined bomber to fly. It used four Lyulka TR-1 turbojets carried on short horizontal pylons ahead and below the wing. The engines did not meet their designed thrust ratings and their fuel consumption was higher than planned.

Interleukin-22 (IL-22) is a recently described IL-10 family cytokine that is produced by T-helper (Th)-17 cells, γδ T cells, NKT cells and newly described innate lymphoid cells (ILCs). Knowledge of IL-22 biology has rapidly evolved since its ...

Interleukin (IL)-22 is a potent mediator of inflammatory responses. The IL-22 receptor consists of the IL-22Rα and IL-10Rβ subunits. Previous studies have shown that IL-22Rα expression is restricted to non-hematopoietic cells in the skin, pancreas, ...

IL-22 is a pleiotropic cytokine that acts in the regulation of host defense, barrier function, and metabolism. This review is focused on its physiological role in mucosal tissues in health and disease.

Dec 31, 2013 · Here, the authors describe the biology of IL-22 and highlight the therapeutic potential of modulating the activity of IL-22 and/or its receptor IL-22R1. Interleukin-22 (IL-22) is a key...

IL-22 or IL 22 or IL22 may refer to: Interleukin 22; Illinois's 22nd congressional district, an obsolete district in the USA; Illinois Route 22, USA; Ilyushin Il-22, a Russian jet bomber aircraft prototype flown in 1947; Ilyushin Il-22, the airborne command post version of …

Nov 12, 2024 · This review delineates the various connections between the IL-22 signaling pathway and autoimmune disease, focusing on the latest understanding of the cellular sources of IL-22 and its effects on various cell types.

Interleukin-22 (IL-22) has important functions in host defense at mucosal surfaces as well as in tissue repair. It is unique as a cytokine that is produced by immune cells, including T-helper (Th) cell subsets and innate lymphocytes, but acts only on non-hematopoietic stromal cells, in …

Oct 31, 2018 · Interleukin 22 (IL-22) is a cytokine secreted by immune cells that specifically acts on epithelial cells. It has been found to have both proinflammatory and anti-inflammatory roles in various tissue sites, such as the liver and GI tract.