Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans, interleukin 10 is encoded by the IL10 gene. [5] IL-10 signals through a receptor complex consisting of two IL-10 receptor-1 and two IL …

The Ilyushin Il-10 (Cyrillic Илью́шин Ил-10, NATO reporting name: "Beast" [3]) is a Soviet ground attack aircraft developed at the end of World War II by the Ilyushin construction bureau. It was also license-built in Czechoslovakia by Avia as the Avia B-33.

Jun 23, 2023 · Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory cytokine, protecting the body from an uncontrolled immune ...

Feb 15, 2010 · Interleukin-10 (IL-10), a cytokine with anti-inflammatory properties, has a central role in infection by limiting the immune response to pathogens and thereby preventing damage to the host.

Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on most hemopoietic cell types.

The authors review the molecular mechanisms regulating IL-10 production and response and describe classic and novel functions of IL-10 in immune and non-immune cells. They further discuss the therapeutic potential of IL-10 in different diseases and ...

IL-10 is one of a family of antiinflammatory cytokines expressed in the skin. The importance of IL-10 in limiting inflammatory damage has been shown in studies of knock-out mice, which develop colitis and arthritis of the joints [86]. Treatment with viral IL-10 showed improved healing in full-thickness murine wound models [87].

The IL-10 family is a family of interleukins. In addition to IL-10, it includes IL-19, IL-20, IL-22, IL-24 and IL-26. [1] Some sources also include the interferons IL-28 and IL-29. [2] The IL-10 family are helical cytokines categorized based on their specific …

To identify essential molecular features of IL-10 required for IL-10 receptor binding, the diverse sequences and structures of the cellular and viral IL-10s were compared, since all share the ability to engage IL-10R1 and IL-10R2 and initiate IL-10 signaling responses (Slobedman et al. 2009).

May 1, 2008 · IL-10 is an anti-inflammatory cytokine. During infection it inhibits the activity of Th1 cells, NK cells, and macrophages, all of which are required for optimal pathogen clearance but also contribute to tissue damage.