
Immunoglobulin G - Wikipedia
IgG is the main type of antibody found in blood and extracellular fluid, allowing it to control infection of body tissues. By binding many kinds of pathogens such as viruses, bacteria, and …
IgG Subclasses and Allotypes: From Structure to Effector Functions
Immunoglobulin G (IgG) is one of the most abundant proteins in human serum, accounting for about 10–20% of plasma protein. It is the major class of the five classes of immunoglobulins in …
What is IgG2a? - Mabtech
What is IgG2a? Immunoglobulin G (IgG) is the most abundant Ig isotype in serum, making up approximately 80% of all serum Immunoglobulins. In mice, the IgG subclasses are defined …
Immunoglobulin G2a Antibody - an overview - ScienceDirect
An Immunoglobulin G2a Antibody is a type of monoclonal antibody that exhibits cytotoxicity against tumor cells by inhibiting DNA synthesis and proliferation, as demonstrated in the …
The solution structure of the human IgG2 subclass is distinct from ...
Human IgG2 antibody displays distinct therapeutically-useful properties compared with the IgG1, IgG3, and IgG4 antibody subclasses. IgG2 is the second most abundant IgG subclass, being …
Properties of mouse and human IgG receptors and their contribution to ...
Jun 14, 2012 · It follows that all activating mouse FcγRs (FcγRI, FcγRIII, and FcγRIV) bind to IgG2a and IgG2b, whereas FcγRIII is the only activating FcγR binding IgG1 and FcγRI the …
Immunoglobulin G2a - an overview | ScienceDirect Topics
Immunoglobulin G2a (IgG2a) is a subtype of the IgG class of antibodies that is predominantly induced in viral and intracellular bacterial infections, playing a key role in the immune response …
IgG subclasses and allotypes: from structure to effector functions
Oct 20, 2014 · Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, …
How different are the functions of IgG2a and IgG2c?
In the past, we performed a range of studies where we compared the targeting behaviour of several rat monoclonal IgG2a and IgG2b antibodies in a fully homologous experimental …
IgG2a Protein Overview - Sino Biological
Know comprehensive IgG2a protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein interaction.