CD31, or platelet endothelial cell adhesion molecule-1 (PECAM-1) is a member of the Ig gene superfamily expressed at high density at the lateral borders of endothelial cells (ECs) and at a …

Platelet endothelial cell adhesion molecule (PECAM-1) also known as cluster of differentiation 31 (CD31) is a protein that in humans is encoded by the PECAM1 gene found on …

Here, we report that another immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing receptor, platelet endothelial adhesion molecule-1 (PECAM1 / CD31), regulates FcγR function, …

Dec 15, 2019 · FcγR-mediated phagocytosis is regulated by the concerted actions of activating FcγR and inhibitory receptors, such as FcγRIIb and SIRPα. In this study, we report that …

We demonstrate that the CD20low/−CD138+CD31+ BM population was highly enriched for antibody-secreting cells with IgG being the predominant isotype (60%), followed by IgA (33%) …

Jun 27, 2016 · We demonstrate that the CD20low/-CD138+CD31+ BM population was highly enriched for antibody-secreting cells with IgG being the predominant isotype (60%), followed …

May 1, 2019 · Abstract. Monocytes and macrophages express Fc-gamma Receptors (FcγR) that engage IgG immune complexes such as antibody-opsonized pathogens or cancer cells

Nov 9, 2010 · We show that loss of CD31 interactions leads to enhanced primary clonal expansion, increased killing capacity, and diminished regulatory functions by T cells. …

Dec 15, 2019 · Scr or CD31 siRNA-nucleofected cells were incubated in control PBS-treated (UT, untreated) or plate-bound IgG for 24 h, and supernatants were analyzed for cytokine content …

Here, we show that CD31 is a key coinhibitory receptor on stimulated DCs, favoring the development of tolerogenic functions and finally resulting in T-cell tolerance. The disruption of …