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1. Type I (IgE-mediated or anaphylactic-type) (def) Mechanism: This is the most common type of hypersensitivity, seen in about 20% of the population. IgE is made in response to an allergen (def) (see Fig. 1 and Fig. 2). In allergic individuals, the levels of IgE may be thousands of times higher than in those without allergies.

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