Interferon beta is a protein that in humans is encoded by the IFNB1 gene. [5] The natural and recombinant protein forms have antiviral, antibacterial, and anticancer properties.

Mar 30, 2025 · IFNB1 (Interferon Beta 1) is a Protein Coding gene. Diseases associated with IFNB1 include Multisystem Inflammatory Syndrome In Children and Secondary Progressive …

Feb 8, 2025 · Gene target information for IFNB1 - interferon beta 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

IFN-beta activates cytotoxic function of human natural killer cells toward IL-27 and poly (I:C) stimulated PC3 and DU145 cells. Early plasma interferon-beta levels as a predictive marker of …

In this study, we used bone marrow–derived macrophages from Ifnb1−/− mice and Ifnar1−/− mice to examine the role of IFN-β and its receptor in the induction of ISG expression by LPS in …

Using siRNA-mediated silencing of several core autophagy molecules and STAT1, we provide evidence that IFNB1 mediates its antiproliferative effects independent of autophagy, while the …

Mar 24, 2023 · Here, we report that malignant blasts from patients with acute myeloid leukemia (AML) release type I IFN via a Toll-like receptor 3 (TLR3)-dependent mechanism that is not …

Feb 8, 2025 · Enables cytokine activity and type I interferon receptor binding activity. Involved in several processes, including negative regulation of Lewy body formation; response to virus; …

Feb 2, 2022 · IFNB1 belongs to the type I inteferon family of cytokines. Binding of IFNB1 to its receptor, IFNAR1 (107450), results in immunoregulation, including antiviral and …

IFNB1 is more potent than interferon-alpha (IFN-alpha) in inducing the apoptotic and antiproliferative pathways required for control of tumor cell growth (PubMed: 14597717).