In immunology, an idiotype is a shared characteristic between a group of immunoglobulin or T-cell receptor (TCR) molecules based upon the antigen binding specificity and therefore structure of …

Each antibody will present multiple idiotopes; the sum of the individual idiotopes is called the idiotype of the antibody. Formation of anti-idiotype antibodies. A single clone of plasma cells …

Jan 19, 2018 · As shown in figure 1, an anti-idiotypic (Anti-ID) antibody binds to the idiotype of another antibody, usually an antibody drug. An idiotype can be defined as the specific …

May 21, 2024 · An idiotype is a set of amino acids that are unique to an antibody and that determine its specificity — in other words, which antigens it will bind to. The study of idiotypes …

Idiotypes are antibodies that recognize different specific epitopes. The thing that determines the idiotype is way at the end of the variable region; it’s composed of a bunch of different idiotopes …

The immunochemical criterion used to classify the idiotype consists of the effect of antigen on the interaction between idiotype and anti-idiotype antibodies. In the case of some idiotypes, this …

Feb 18, 2024 · Allotype refers to genetic variations in the constant region of antibodies, differing among individuals of the same species. Idiotype involves unique antigen-binding sites of …

Feb 18, 2024 · While the isotype determines the antibody's role within the immune response, the idiotype determines its specificity for a particular antigen. This dual characterization is …

Idiotypy is an important concept with significant practical implications for the manipulation of B- and T-cell clones. However, this potential depends on a correct identification of idiotypy and …

The term idiotype is used to describe the epitope(s) formed by the unique three-dimensional antigen binding end of each monoclonal antibody. The definition is based on serological …