Oct 10, 2018 · The Initiation of Dialysis Early Versus Delayed in the Intensive Care Unit (IDEAL-ICU) trial was a randomized, controlled, open-label, multicenter trial that was designed to compare an early...

Nov 9, 2018 · Acute kidney injury is a common occurrence in patients with septic shock. The decision as to when to start renal replacement therapy is controversial. patients with septic shock and severe acute kidney injury, does early vs. delayed renal replacement therapy improve 90 …

Mar 27, 2019 · Published in 2018, the Initiation of Dialysis Early Versus Delayed in the Intensive Care Unit (IDEAL-ICU) trial was a multicenter, randomized, open-label trial designed comparing early- vs. delayed-initiation strategies for RRT among ICU patients with septic shock and AKI.

IDEAL-ICU was a multicenter trial that sought to enroll 864 critically ill patients in a trial of early versus delayed KRT initiation, which would have made it the largest trial to date to investigate this question.

Jul 14, 2016 · Impact on mortality of the timing of renal replacement therapy in patients with severe acute kidney injury in septic shock: the IDEAL-ICU study (Initiation of Dialysis Early versus Delayed...

the Intensive Care Unit (IDEAL-ICU) trial was a randomized, controlled, open-label, multicenter trial that was designed to compare an early strategy with a delayed...

Aug 27, 2021 · The ELAIN study showed a survival benefit with early versus late KST, whereas the AKIKI, IDEAL-ICU, FST, and STARRT-AKI RCTs did not replicate these findings. More recently, the AKIKI2 trial showed that a more delayed approach is …

The recently published Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis (IDEAL-ICU) trial, a multicentre RCT involving 488 septic patients, found no significant difference in 90-day mortality between early RRT (<12 hrs of Failure stage of RIFLE criteria, comparative to KDIGO stage 3) and delayed RRT (>48 hrs ...

Aug 13, 2020 · IDEAL- ICU. The results between ELAIN and AKIKI were divergent with key differences, and they did not fully answer the question of the ideal timing of RRT initiation. Two years later in 2018, Barbar and colleagues published the IDEAL-ICU trial.

Dec 3, 2018 · The IDEAL-ICU study reports no mortality benefit of early versus delayed initiation of renal replacement therapy (RRT) in patients with early septic shock and acute kidney injury.