Jun 1, 2017 · We here propose the evaluation method of undifferentiated iPSC culture process by visualizing the quantitatively measured morphological data of iPSC colonies (Schematic illustration of our concept is shown in Fig. 1).

Illustration summarizing the different methods for iPSC generation including non-integrative vectors, integrative methods, transient expression of small molecules, and integrative vectors that...

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As iPSCs serve tremendous correction potentials for various diseases, we highlight the successes and challenges of iPSCs in cell replacement therapy and the synergy of iPSCs and clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene …

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Mar 1, 2023 · Human induced pluripotent stem cells (iPSC) have demonstrated massive potentials for use in regenerative and personalized medicine due to their ability to expand in culture and differentiate into specialized cells with therapeutic benefits.

induced pluripotent stem cell (iPS cell) and regenerative medicine, vector illustration. Cell Therapy Development - Cell Engineering and Cell Programming - Conceptual Illustration.

In the illustration, a somatic cell has had OSKM exogenously expressed to initiate the reprogramming mechanism. The result is an iPSC, which in proper culture conditions can be induced to differentiate into any cell type.

In this study, we aimed to identify the transcription factor regulating production of human PDL cell-derived ECM, which is responsible for the generation of iPDLSCs.

The repository contains sample iPSC images for classifier models to assess pluripotency.