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See all on WikipediaInterleukin 1 beta - Wikipedia
Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene. There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β … See more
• Smirnova MG, Kiselev SL, Gnuchev NV, Birchall JP, Pearson JP (2003). "Role of the pro-inflammatory cytokines tumor necrosis factor … See more
Increased production of IL-1β causes a number of different autoinflammatory syndromes, most notably the monogenic conditions referred to as See more
Because many authors of scientific manuscripts make the minor error of using a homoglyph, sharp s (ß), instead of beta (β), mentions of "IL-1ß" [sic] often become "IL-1ss" [sic] upon automated transcoding (because ß transcodes to ss). This is why so many mentions … See more
• IL1B+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain. See moreWikipedia text under CC-BY-SA license Understanding the mechanism of IL-1β secretion - PMC
The cytokine interleukin-1β (IL-1β) is a key mediator of the inflammatory response. Essential for the host-response and resistance to pathogens, it also exacerbates damage during chronic disease and acute tissue injury. It is not …
Interleukin 1beta - an overview | ScienceDirect Topics
Learn about the role of interleukin 1beta (IL-1β), a cytokine that regulates inflammation, in obesity, PCOS, endometriosis, and fertility. Find chapters and articles from various journals and books …
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Overview of the IL-1 family in innate inflammation and …
IL-1β is the most studied member of the IL-1 family due to its role in mediating autoinflammatory diseases. 4 Unquestionably, IL-1β evolved to assist host defense against infection 5 and this landmark study established how a low …
The role of interleukin-1 beta in inflammation and the potential of ...
Mar 1, 2025 · This review summarizes the role of IL-1 beta in various inflammatory diseases and the current and upcoming treatments that target it. It also explains the mechanism of IL-1 beta …
Mechanisms of interleukin-1beta release - PubMed
Interleukin-1beta (IL-1beta) is a potent proinflammatory cytokine that initiates and amplifies a wide variety of effects associated with innate immunity and host responses to microbial invasion …
Role of interleukin-1β during pain and inflammation - PMC
IL-1β is a pro-inflammatory cytokine that has been implicated in pain, inflammation and autoimmune conditions. This review will focus on studies that shed light on the critical role of …
Interleukin-1 beta (IL1B) - Abcam
IL-1 beta is produced and released by various types of immune and non-immune cells in rapid response to inflammatory signals. Read our IL-1 beta target tip to learn more about how to …
IL-1β + macrophages and the control of pathogenic inflammation …
Mar 31, 2025 · IL-1β + TAMs engage in long-range interactions with cells in the bone marrow, influencing hematopoiesis and systemic immunity throughout disease initiation, evolution, and …
Interleukin-1beta (IL-1beta) processing pathway - PubMed
Jan 19, 2010 · Here, we describe the essential components of the NALP3-inflammasome that control processing and release of IL-1beta. The innate immune system senses molecular …
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