Mar 30, 2025 · This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and …

Interferon gamma receptor 1 (IFNGR1) also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene. [5] [6] [7]

The interferon-gamma receptor (IFNGR) protein complex is the heterodimer of two chains: IFNGR1 and IFNGR2. It binds interferon-γ, the sole member of interferon type II.

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic …

Aug 12, 2021 · Targeting IFNGR1 stability, including palmitoylation, may be a promising approach to overcome intrinsic ICB resistance in patients with colorectal cancer.

IFNGR1 is the ligand-binding subunit. Branca and Baglioni (1981) concluded that types I and II interferons have different receptors. Celada et al. (1985) demonstrated and partially …

Feb 8, 2025 · This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and …

Apr 13, 2020 · We demonstrate that heterozygous deletion of Elf5 downregulates FBXW7—a ubiquitin ligase involved in proteasomal degradation of IFN-γ receptor 1 (IFNGR1).

Receptor subunit for interferon gamma/INFG that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation …

2 days ago · Here, we report an AD IFNGR1 variant in a family with MSMD and demonstrate the ubiquitous nature of IFN-γR1 expression and the capacity for dominant-negative IFN-γR1 …