Interferons (IFN s, / ˌɪntərˈfɪərɒn / IN-tər-FEER-on[1]) are a group of signaling proteins [2] made and released by host cells in response to the presence of several viruses. In a typical …

Aug 2, 2019 · High-burden uptake of apoptotic cells is associated with loss of phagocytosis in resolution phase macrophages. Here, using a transcriptomic analysis of macrophage subsets, …

Interferon Type I (α/β/δ...) The molecular structure of human interferon-beta (PDB: 1AU1 ). The type-I interferons (IFN) are cytokines which play essential roles in inflammation, …

Type I IFNs impact B-cell function through a variety of mechanisms, including effects on receptor engagement, Toll-like receptor expression, cell migration, antigen presentation, cytokine …

Mar 13, 2012 · Here, we review the functions of IFN-β in innate and adaptive immunity. We also discuss the activation and influence of IFN-β on myeloid cell types, including monocytes and …

Since the discovery of the protein “interferon” over 50 years ago, IFNβ, an antiviral cytokine has been well studied. In particular the pathways inducing this cytokine during viral infection have …

Interferon beta is a protein that in humans is encoded by the IFNB1 gene. [5] . The natural and recombinant protein forms have antiviral, antibacterial, and anticancer properties. Interferon …

Jan 1, 2016 · Interferon beta (IFNβ) is a cytokine that is naturally produced by the immune system in response to biological and chemical stimuli. It signals by binding to the heterodimeric type I …

Feb 8, 2025 · Title: IFN-β activates cytotoxic function of human natural killer cells toward IL-27 and poly (I:C) stimulated PC3 and DU145 cells. Title: Early plasma interferon-β levels as a …

Jun 12, 2007 · Interferon-beta (IFN-beta) is a polypeptide, normally produced by fibroblasts, that has antiviral and antiproliferative effects. Binding of IFN-beta to its receptor induces a complex …