HPMCAS (here on often referred as AS) is an enteric polymer composed of cellulose back bone with a substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups (Fig. 2). You …

Dec 1, 2008 · In this paper, we discuss the discovery and development of a spray-dried solid amorphous dispersion technology based on hydroxypropyl methylcellulose acetate succinate …

Shin-Etsu AQOAT® (hypromellose acetate succinate or HPMCAS) is an excellent polymer for enteric coating of solid dosage forms (tablets, pellets, capsules). Since the introduction of …

Aug 1, 2022 · HPMCAS is an effective polymer for the creation of ASD with dual functionality: solubilization of poorly soluble drugs, promotion of rapid dissolution in the intestinal medium, …

Hydroxypropyl methylcellulose acetate succinate (HPMCAS) has multi-disciplinary applications spanning across the development of drug delivery systems, in 3D printing, and in tissue …

In this study, the impact of drug and hydroxypropyl methylcellulose acetate succinate (HPMCAS) grades physicochemical properties on extrusion process, dissolution and stability of the hot …

been prepared using the polymer hydroxypropyl methylcellulose acetate succinate (HPMCAS). For a variety of drug structures, these SDDs provide supersat.

Shin-Etsu AQOAT® is the leading polymer in solid dispersion technology. It is suitable for spray-drying, hot melt extrusion, co-precipitation and other techniques. There are more than 14 …

AquaSolve HPMCAS is a mixture of acetic acid and monosuccinic acid esters of hydroxypropylmethylcellulose. AquaSolve HPMCAS is used as a solid dispersion polymer for …

Oct 11, 2013 · With the increased use of amorphous dispersions, hypromellose acetate succinate (HPMCAS) has emerged as a commonly used excipient for formulation design. This unique …