Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify …

The Hox genes are a set of transcription factor genes that exhibit an unusual property: They provide a glimpse of one way in which gene expression is translated into the many different …

Nov 20, 2024 · We analyse HOX gene expression across cell types during development, finding that neural-crest derivatives unexpectedly retain the anatomical HOX code of their origin while …

Hox genes play many more roles in vertebrate development. They help specify the difference between an arm and a leg, as well as a pinky and a thumb. In the nervous system, their …

Indeed, one of the most remarkable pieces of evidence for deep homologies among all the animals of the world is provided by the Hox genes. As mentioned in Chapter 11, not only are …

Dec 1, 2004 · In this review, the origin of the Hox and ParaHox gene clusters by duplication of a ProtoHox gene cluster, and the changes in their gene numbers in major Metazoan Transitions …

Hox genes encode evolutionarily conserved transcription factors that are essential for the proper development of bilaterian organisms. Hox genes are unique because they are spatially and …

In this commentary, we highlight recent reports that have provided novel insight into the origins of the mammalian Hox cluster, the role of Hox genes in the generation of a limbless body plan, …

Hox genes are members of the homeotic transcription factor family that play a key role in controlling the body plan along the cranio-caudal axis (also referred to as anterior–posterior), …

HOX genes comprise a family of highly conserved, regulatory genes that encode transcription factors, which control the activity of other, functionally contiguous genes in the context of …