Oct 24, 2023 · What is Honeycomb Lung? Honeycomb Lung is not a disease in itself but a characteristic pattern seen in various lung conditions, most commonly in idiopathic pulmonary fibrosis (IPF). This honeycombing pattern resembles, as the name suggests, a honeycomb’s hexagonal structure.

Mar 25, 2025 · Honeycombing describes small adjacent subpleural cystic structures in the context of established pulmonary fibrosis with destruction of lung architecture and traction bronchiolectasis. A single layer of cysts is now considered sufficient to apply this descriptor in the correct context 11.

Apr 3, 2025 · Click here to learn more about honeycombing on a patient's HRCT, which is often an indicator of usual interstitial pneumonia (UIP).

Sep 20, 2017 · An increased frequency of bronchiolar histotypes in lung carcinomas appears to be associated with IPF, in which abnormal bronchiolar proliferation occurs in transformed small airways in...

Honeycombing is a key CT characteristic in IPF and is defined as clustered cystic airspaces of comparable diameters (∼3–10 mm) that are usually subpleural with thick, well-defined walls (5).

Nov 23, 2012 · Although the definition is straightforward, diagnosing honeycomb lung in IPF or UIP is sometimes not easy for radiologists. For instance, in a study of 314 cases of IPF, the interobserver agreement regarding the presence of honeycomb lung ranged from 0.21 to 0.31, which indicates rather poor agreement . This variation could originate from the ...

First, it establishes the presence of lung fibrosis. Second, it allows the recognition of specific patterns, namely typical and probable Usual Interstitial Pneumonia (UIP) pattern obviating the need for tissue confirmation in the appropriate clinical context.

IPF is recognized on high-resolution computed tomography by peripheral, subpleural lower lobe reticular opacities in association with subpleural honeycomb changes. IPF is associated with a pathological lesion known as usual interstitial pneumonia (UIP).

May 23, 2016 · The diagnostic and prognostic impact of traction bronchiectasis on high resolution CT scan (HRCT) in patients suspected to have idiopathic pulmonary fibrosis (IPF) is increasing significantly. Recent data demonstrated that cysts in honeycombing areas are covered by epithelium expressing bronchiolar markers.

Feb 8, 2019 · Prognostic evaluation in idiopathic pulmonary fibrosis (IPF) may be important as it can guide management decisions, but the potential role of honeycomb changes in providing information about outcome and survival of patients with IPF, particularly if diagnosed using cryobiopsy, has not been evaluated.