HI-Q Environmental Products Company (HI-Q) is a leading manufacturer of Air Sampling & Radiation Monitoring Equipment, Systems and Services since 1973. We are an ISO …

p21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclin-CDK2, -CDK1, and -CDK4 /6 complexes, and thus functions …

Our study illuminates that immediate-early cell-autonomous reactions to cellular stress are coordinated with cell non-autonomous responses through p21-mediated changes in the Rb …

Here we report that stimulation of epithelial or fibroblastic cells with G protein-coupled receptor agonists, including angiotensin II or bombesin, induced rapid and persistent PKD1 …

Through this approach, we identified p21 (Cdkn1a), which encodes the cyclin-dependent kinase (CDK) inhibitor p21, and conducted an in-depth analysis of its functions from the time cells first …

Aug 6, 2024 · Clearance of p21 high cells reduces inflammation and alleviates age-related transcriptomic signatures of various tissues. These findings demonstrate the feasibility of …

In this Review we discuss recent advances concerning the complex role of p21 in the development of cancer. We describe the various effector functions of p21 that allow it to exert …

HI-P21 temperature recorder’s scanning occurs every 10 seconds. Temperature is recorded to user tags 0 and 1 for sensor A(1) and B(2) correspondingly. Temperature is transmitted in …

To explore the importance of ROS in the irreversible growth arrest/senescence phenotype induced by p21, we examined the effect of exposure to 10 mM NAC on colony formation …

May 5, 2005 · We show that silencing a single cell cycle checkpoint protein, p21, increased the gene transduction efficiency while retaining the multipotentiality of stem/progenitor cells. The …