Cycloheximide (CHX), an inhibitor of protein synthesis, has been reported to prevent cell death in a wide variety of cell types and produced by different apoptotic stimuli. However, the …

CHX Protects HepG2 Cells from Apoptosis Induced by Serum Deprivation. HepG2 cells were cultured in MEM with 10% FBS or without the 10% FBS (serum deprivation medium) and …

Oct 2, 2021 · To explore the potential role of metformin in disrupting one-carbon metabolism to overcome resistance to MTX, we established MTX-resistant hepatocarcinoma cell lines …

... experiments, we found that CHX increased MDR1 mRNA levels in HepG2 cells in a dose-and time-dependent manner, reaching a 7-fold induction after exposure to 25 g/ml CHX for 24 h …

A and B, HepG2 cells were pretreated with 30 g/ml cycloheximide for 2 h, then treated with or without 100 M DMSO or t-BHQ alone for the indicated time points. Cells were harvested, and …

Current data suggests that hepatocyte apoptosis is an essential feature contributing to several chronic liver diseases. It has been shown that IL-10 has diverse and potentially pleiotropic...

Dec 1, 2021 · We found that Bcl-3 deficiency had no effect on TNFR1 expression in vivo after TNF/D-GalN treatment (Fig. S4A) or in tet-on HepG2 and LO2 cells stimulated with TNF/CHX …

Feb 10, 2023 · Cycloheximide (CHX) chase analysis showed that OGT knockdown accelerated the degradation of the YTHDF2 protein, while silencing of OGA decelerated its rate of decay …

Both protein and RNA synthesis were inhibited in Hep G2 cells by the concentrations of CHX and Act D associated with TNF cytotoxicity. Hep G2 cells pretreated with TNF alone and later …

Apr 15, 2016 · We previously found that the SphK1 inhibitor II (SKI II), suppresses the cell growth and induces apoptosis in human hepatoma HepG2 cells. However, the precise regulatory …