Heme oxygenase 1 protects human colonocytes against ROS formation ...
Sep 23, 2020 · Hemin catalyzed the formation of reactive oxygen species (ROS) and induced oxidative DNA damage as well as DNA strand breaks in both HCEC and CRC cells. In …
Mitochondrial reactive oxygen species and heme, non-heme iron ...
Mar 30, 2021 · These findings indicate that mitochondrial reactive oxygen species is associated with iron-related oxidative reactions. Recently, a mitochondria-specific iron transporter, …
Role of Heme Oxygenase as a Modulator of Heme-Mediated …
Heme, besides being an often-quoted generator of oxidative stress, plays also an important role as a signaling molecule. Heme controls the anti-oxidative defense, circadian rhythms, activity …
Heme Oxygenase-1 Signaling and Redox Homeostasis in …
Heme-oxygenase is the enzyme responsible for degradation of endogenous iron protoporphyirin heme; it catalyzes the reaction’s rate-limiting step, resulting in the release of carbon monoxide …
Heme oxygenase-1: redox regulation of a stress protein in lung ... - PubMed
In higher organisms, heme oxygenase-1 (HO-1) has been widely studied as a model for redox-regulated gene expression. Expression of HO-1 responds to chemical and physical agents that …
ROS-mediated heme degradation and cytotoxicity induced by iron ... - PubMed
It was revealed that ZVFe NP interaction resulted in heme displacement and degradation and induction of protein cabonylation. It was also shown that ZVFe NPs impaired the complexity of …
Heme Oxygenase in the Regulation of Vascular Biology: From …
Heme oxygenases (HOs) are the rate-limiting enzymes in the catabolism of heme into biliverdin, free iron, and carbon monoxide. Two genetically distinct isoforms of HO have been …
Regulation of ROS Production and Vascular Function by Carbon …
Aug 9, 2012 · Carbon monoxide (CO) is a gaseous molecule produced from heme by heme oxygenase (HO). CO interacts with reduced iron of heme-containing proteins, leading to its …
Blood Meal-Derived Heme Decreases ROS Levels in the Midgut of
Mar 17, 2011 · Here, we show that reactive oxygen species (ROS) are present in the gut epithelia of sugar-fed mosquitoes and are drastically reduced after blood feeding through a mechanism …
Heme oxygenase 1 protects human colonocytes against ROS …
Sep 23, 2020 · Hemin catalyzed the formation of reactive oxygen species (ROS) and induced oxidative DNA damage as well as DNA strand breaks in both HCEC and CRC cells. In …
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