Dec 11, 2014 · Effect of Dual RAAS Blockade and Intensive BP Lowering on Risk of End-Stage Kidney Disease and Death in Autosomal Dominant Polycystic Kidney Disease: Long-term …

Jun 8, 2022 · The HALT Progression of Polycystic Kidney Disease (HALT PKD) studies were two simultaneous multicenter clinical trials designed to test the efficacy of interruption of the renin …

HALT-PKD is the first large multicenter interventional trial of ADPKD that is testing both a novel kidney structural endpoint in early disease (study A) and more conventional kidney functional …

Dec 11, 2014 · The Halt Progression of Polycystic Kidney Disease (HALT-PKD) trials were designed to have sufficient power to ascertain the effect of intensive blockade of the RAAS …

The target blood pressure should be below 130/80 mm Hg. Based on new data from the HALT-PKD studies, a greater blood pressure reduction can be recommended, provided that patients …

Aug 15, 2024 · Because the HALT-PKD trials ended in 2014, the shorter post-trial follow-up duration and the higher eGFR of participants in HALT-PKD A, where the number of cases of …

Jan 3, 2018 · We used data from the recently completed Halt Progression of Polycystic Kidney Disease (HALT-PKD) trials 16,17 to test the hypothesis that GFR decline in ADPKD is not …

HALT PKD will evaluate potential benefits of rigorous BP control and inhibition of the renin-angiotensin-aldosterone system on kidney disease progression in ADPKD.

1 day ago · But right now, the main achievable goal is to slow or halt the progression of PKD through lifestyle and medication. Lifestyle includes maintaining a healthy weight, eating a …

The HALT PKD trial in early autosomal dominant polycystic kidney disease (ADPKD) showed that intensive control of systolic blood pressure to 95-110 mmHg was associated with a 14% …