The hemagglutination assay or haemagglutination assay (HA) and the hemagglutination inhibition assay (HI or HAI) were developed in 1941–42 by American virologist George Hirst as methods for quantifying the relative concentration of viruses, bacteria, or antibodies.

Mar 28, 2023 · The hemagglutination assay (HA assay) takes advantage of the unique ability of the flu virus’s hemagglutinin (HA) protein to make red blood cells stick together (agglutinate). By measuring how much these cells agglutinate, we can estimate the amount of flu virus in a sample.

Dec 13, 2022 · Hemagglutination assay (HA) is a type of immunoassay in which erythrocytes are used as carrier particles and are commonly preferred for serological diagnosis of various infections.

The hemagglutination assay (HA) is a tool used to screen cell culture supernatant or amniotic-allantoic fluid harvested from embryonated chicken eggs for hemagglutinating agents, such as type A influenza. The HA is not an identification assay, as other agents also have hemagglutinating properties.

Oct 12, 2023 · In 1941-1942, an American virologist named George Hirst developed the hemagglutination assay (HA) and the hemagglutination inhibition test (HI or HAI), procedures for detecting the relative concentration of viruses, bacteria, or antibodies.

Apr 7, 2023 · The hemagglutination assay (HA assay) is a simple, quick, and cost-effective method for estimating the amount of influenza virus in a sample. It leverages the influenza virus’s hemagglutinin (HA) protein, which causes red blood cells to agglutinate or stick together.

Jun 3, 2017 · The main purpose of the assay is to estimate HA titre for the unknown viral sample. The basis of this assay is the ability of viral haemaglutinin to bind with the sialic acid present on the receptors of surface of the red blood cells causing haemagglutination.

May 17, 2024 · What is Hemagglutination assay? George Hirst, an American virologist, created the hemagglutination assay or haemagglutination assay (HA) and the hemagglutination inhibition test (HI or HAI) in 1941–1942 as procedures for determining the relative concentration of viruses, bacteria, or antibodies.

The HA assay (also called HA titration) is performed to quantify the virus particles necessary for hemagglutination, and is recorded in HA units. A "unit" of hemagglutination is an operational unit dependent on the method used for HA titration and is not a …

Hemagglutination inhibition test is widely used for the diagnosis of infection caused by orthomyxoviruses (influenza), paramyxoviruses (measles, mumps), mononucleosis, arboviruses-togaviruses (including rubella), flaviviruses, and bunyaviruses.