Aug 15, 2020 · Henoch-Schönlein purpura, now called immunoglobulin A (IgA) vasculitis, is a systemic, immune complex–mediated, small-vessel leukocytoclastic vasculitis characterized by nonthrombocytopenic...

Oct 28, 2024 · Immunoglobulin A vasculitis (IgAV; formerly called Henoch-Schönlein purpura [HSP]) , is the most common form of systemic vasculitis in children, with an incidence range of 3 to 27 per 100,000 . Ninety percent of cases occur in the pediatric age group.

Sep 26, 2023 · IgA vasculitis, formerly known as Henoch-Schönlein purpura, is a complex immune-mediated vasculitis characterized by the involvement of small blood vessels in various organ systems. IgA vasculitis primarily affects the small vessels of the joints, kidneys, gastrointestinal tract, skin, and, in rare instances, the central nervous system and lungs.

Sep 21, 2021 · Lab tests. No single laboratory test can confirm Henoch-Schonlein purpura, but certain tests can help rule out other diseases and make a diagnosis of Henoch-Schonlein seem likely. They may include: Blood tests. Your blood may be tested if your diagnosis isn't clear based on your signs and symptoms. Urine tests.

Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of HSP. The tetrad of purpura, arthritis, kidney inflammation, and abdominal pain is often observed. However, all four elements of this tetrad are not required for diagnosis.

most common vasculitis in children but can also occur in adults. Diagnostic testing is required only to exclude other etiologies of purpura, to identify renal in. olvement, and, if indicated, to...

There is no specific diagnostic test available for HSP. Platelet count, coagulation studies such as PT, aPTT, and BT are done to rule out other diseases like coagulopathies. They are usually normal. Urinalysis is done to check for any blood in the urine or proteinuria for renal involvement.

Jun 28, 2023 · Henoch-Schönlein purpura (HSP; also referred to as Schönlein-Henoch purpura, anaphylactoid purpura, or purpura rheumatica) is an acute immunoglobulin A (IgA)–mediated disorder...

HSP is the most common vasculitis of childhood. It most commonly affects children 2-8 years of age. Usually affects large joints of lower limbs. Rarely upper limbs. If prescribing oral prednisolone, give 1-2 mg/kg/day (maximum 60 mg/day) or IV methylprednisolone 0.8-1.6 mg/kg/day (maximum 1 g/day) while symptoms persist.

Jul 15, 2024 · Henoch-Schönlein purpura (HSP) is a disease that inflames small blood vessels. The inflammation causes blood vessels in the skin, intestines, kidneys, and joints to start leaking. The main...