iSPE-HILIC cartridges are designed for the purification of polar and hydrophilic compounds using Hydrophilic Interaction Liquid Chromatography (HILIC). The packed stationary phases are …

HILIC can be described as a variation of Reversed Phase Liquid Chromatography (RPLC) performed using a polar stationary phase. The mobile phase employed in HILIC is highly …

Publication outlines a HILIC-based clean‐up method enabling complete separation of polar lipids containing four fatty acyl residues from non-polar lipid classes using iSPE® HILIC columns.

GlycoWorks HILIC SPE offers a robust, reliable solution for cleanup and concentration of glycans from complex matrices. Its application during the sample preparation of 2-AB labeled glycans …

Here, we demonstrated the glycopeptides enrichment efficiency of iSPE®-HILIC material for glycoproteomics application using a well characterised glycoprotein standard.

Dec 21, 2016 · We can confidently attempt and optimize HILIC at the stage of SPE within a given method, where HILIC of extracts in the LC dimension may not work with adequate …

Apr 1, 2024 · We developed a sensitive method for N-glycan characterization using procainamide (ProcA) labelling and online solid phase extraction (online SPE). N-glycans were enzymatically …

HILICON offers novel UHPLC/HPLC columns and SPE cartridges/plates for analysis of polar compounds in HILIC (hydrophilic interaction liquid chromatography) mode.

Jun 1, 2014 · To solve this problem, hydrophilic interaction liquid chromatography-solid phase extraction (HILIC-SPE) directly combined with protein precipitation (PPT) was developed for …

This application brief demonstrates the benefits of using HILIC as an ideal separation mode for glycans as well as the robustness of HILIC in an SPE format.