A high haemoglobin glycation index (HGI) is associated with greater risk for hypoglycaemia and chronic vascular disease. Standardizing how the HGI is calculated would normalize results between research studies and hospital laboratories and ...

This study investigated the prognostic importance of the hemoglobin glycation index (HGI) for macrovascular and microvascular outcomes, mortality, and hypoglycemia occurrence in a type 2 diabetes cohort and compared it to glycated hemoglobin ...

Hemoglobin glycation index (HGI) is the difference between observed and predicted glycated hemoglobin A1c (HbA 1c), derived from mean or fasting plasma glucose (FPG).

Results: Changes in HGI were observed at 12 months after insulin initiation and stabilized by 24 months for the whole cohort and insulin-naive patients. There were significant differences in MACE risk between baseline HGI tertiles; participants with high HGI were at highest risk (low vs high, HR: 0.73 (0.61 to 0.87) 95% CI; moderate vs high, HR ...

Jun 1, 2020 · Multiple studies confirm that high HGI is associated with greater risk for iatrogenic hypoglycemia in diabetes patients and chronic vascular disease in diabetic and nondiabetic populations.

A high hemoglobin glycation index (HGI) has been repeatedly associated with greater risk for hypoglycemia in people with diabetes and greater risk for chronic vascular disease in people with or without diabetes. This review explores how different sources of analytical and biological variation in HbA …

Sep 23, 2021 · We used data from the Vitamin D and Type 2 Diabetes (D2d) study to calculate HGI, to identify HGI-associated variables, and to determine how HGI affects prediabetes and diabetes diagnosis.

Aims: A high haemoglobin glycation index (HGI) is associated with greater risk for hypoglycaemia and chronic vascular disease. Standardizing how the HGI is calculated would normalize results between research studies and hospital laboratories and …

Aug 29, 2020 · At seven years of follow-up, patients in the high HGI group (‘higher-than-predicted HbA1c’) had three times greater risk of retinopathy (30% vs. 9%, p < 0.001) and six times greater risk of nephropathy (6% vs. 1%, p < 0.001) compared with the low HGI group.

Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which ...