Hemoglobin D has the basic structure and composition of normal adult hemoglobin. It is a globular protein containing prosthetic (non-protein) group called heme. There are four individual peptide chains, namely two α- and two β-subunits, each made …

Hemoglobin D is a result of a mutation in the one or both of the Beta-chains that make up hemoglobin molecules. Having one gene effected is referred to as trait; having two is referred to as homozygous "disease" although the symptoms of this disease are mild.

People with hemoglobin D trait have both normal hemoglobin A and abnormal hemoglobin D in red blood cells. Learn about hemoglobin D and how it is inherited.

Hb D attains clinical significance in association with either β thalassemia or HbS. We describe 12 patients, 9 from South Indian population (three cases of Hb D trait and six cases of Hb SD) and 3 from West Bengal (one case homozygous HbDD, one …

A person with hemoglobin D trait (Hb AD) has one copy of the gene that makes the usual hemoglobin (Hb A), and one copy that makes hemoglobin D (Hb D). Hb D is a type of hemoglobin that can cause an inherited blood condition when combined with a hemoglobin other than Hb A.

What is hemoglobin D trait? Hemoglobin D trait means that your child has inherited one gene for the usual hemoglobin (A) from one parent and one gene for hemoglobin D from the other parent.

This topic discusses genetic variants in globin genes. This includes especially common variants that produce hemoglobin (Hb) C, D, E, and others. An approach to Hb C genetic test results is presented separately. (See "Gene test interpretation: Hemoglobin C (Hb C) variant in the hemoglobin beta locus (HBB)".)

Summarized below are the four most commonly encountered hemoglobin patterns that involve hemoglobin D. . Hemoglobin D trait results when the gene for hemoglobin D is inherited from one parent and a hemoglobin A gene from the other. This …

Hemoglobin D trait is an inherited condition that afects the hemoglobin in your red blood cells. Hemoglobin is a protein in red blood cells. The job of hemoglobin is to carry oxygen throughout the body. Red blood cells with normal hemoglobin (A) are flexible and doughnut shaped. Red blood cells with abnormal hemoglobin (D) are smaller than normal.

This is an edited version of the Haemoglobin D trait leaflet for patients. Read now.