Itchy skin, dry mouth, diarrhoea, dry eyes, reduced vitality, and psychological stress are the most commonly reported symptoms of GVHD. What are the complications of graft-versus-host disease? Impaired sleep due to itchy skin involvement. Genital involvement can …

Cutaneous manifestations are the most common and are often the presenting sign of graft-versus-host disease (GVHD). Cutaneous GVHD may mimic well-known inflammatory and autoimmune disorders.

Aug 11, 2006 · Early on, the skin lesions of cGHVD are often subtle and the progression is insidious, characterized by the development of marked xerosis (skin dryness), follicular prominence (Figure 1), and ichthyosis (fish scale-like skin) (Figure 2).

Acute and chronic graft-versus-host disease (GVHD) are multisystem disorders that are complications of hematopoietic cell transplant (HCT). Skin involvement is common, and mucosal, hair, or nail abnormalities may also occur.

Mar 28, 2025 · The skin is assessed based on the body surface area of involvement and the type of lesions/rash noted. The mouth, eyes, gastrointestinal tract, liver, lungs, genital tract, joints, and fascia can also be involved. 17.3.1 Acute GvHD

Clinical manifestation of the acute GvHD (aGvHD) is limited to erythematous maculopapular rash and oral mucosal lesions while the chronic form manifests in a wider range in a localized area or disseminated including involvement of nail, scalp and genital area.

Jun 10, 2021 · Dermatologic manifestations are an important aspect of graft versus host disease (GVHD). Because the skin often is the earliest organ affected in GVHD, dermatologists are crucial members of...

Sep 1, 2024 · Cutaneous manifestations of acute skin GVHD include a morbilliform eruption (Figure 1 A), which can progress to desquamation and bullae formation in severe (e.g., grade IV) cases (Figure 1 B) [19].

Oct 10, 2023 · Chronic GVHD affects primarily the skin; however, nearly all organ systems can be involved (mucous membranes, liver, lung, eye, joints and fascia, gastrointestinal tract, genitalia) (Blood 2012;120:2545)

Sep 20, 2023 · The skin is the outermost mechanical barrier where dynamic immune reactions take place and is the most commonly affected site in both acute and chronic graft-versus-host disease (GVHD).