Mar 30, 2025 · GRIP1 (Glutamate Receptor Interacting Protein 1) is a Protein Coding gene. Diseases associated with GRIP1 include Fraser Syndrome 3 and Fraser Syndrome 1. Among its related pathways are Transmission across Chemical Synapses …

Glutamate receptor-interacting protein 1 is a protein that in humans is encoded by the GRIP1 gene. [5][6]

The GRIP1 gene provides instructions for making a protein that is able to attach (bind) to other proteins and is important for moving (targeting) proteins to the correct location in cells. Learn about this gene and related health conditions.

Feb 8, 2025 · GRIP1 splice forms interact with gephyrin and play a role in synaptic function at GABAergic and glycinergic synapses in cultured hippocampal neurons. Clinical trial of gene-disease association and gene-environment interaction.

Jul 28, 2016 · Here, we show that GRIP1 facilitates macrophage programming in response to IL4 via a GR-independent pathway by serving as a coactivator for Kruppel-like factor (KLF)4—a driver of tissue-resident...

Feb 8, 2025 · GRIP1 was identified as one of the most important differentially expressed, topologically significant proteins in the protein-protein interaction network in Alzheimer's disease.

Glutamate receptor-interacting protein (GRIP) refers to either a family of proteins that bind to the glutamate receptor or specifically to the GRIP1 protein within this family. Proteins in the glutamate receptor-interacting protein (GRIP) family have been shown to interact with GluR2, a common subunit in the AMPA receptor. [1] .

A search for possible coactivators for steroid hormone receptors resulted in identification of glucocorticoid receptor interacting protein 1 (GRIP1). The complete coding sequence for …

Aug 9, 2012 · Grip1 can visibly interact with Fras1 and is required for the localization of Fras1 to the basal side of cells. In one animal model of Fraser syndrome, the 'eye-blebs' (eb) mouse, Grip1 is disrupted by a deletion of 2 coding exons.

Sep 20, 2020 · Here we show that glutamate receptor interacting protein 1 (GRIP1), an AMPAR-binding protein shown to regulate the trafficking and synaptic targeting of AMPARs, is required for LTP and learning and memory.