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GPS2 (G protein pathway suppressor 2) is a protein that in humans is encoded by the GPS2 gene. It is involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. Diseases associated with GPS2 include liposarcoma and hepatitis C virus. GPS2 is a protein coding gene. Its related pathways include chromatin organization and activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3.
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GPS2 (gene) - Wikipedia
G protein pathway suppressor 2 is a protein that in humans is encoded by the GPS2 gene. This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) si…
Wikipedia
https://en.wikipedia.org/wiki/GPS2_(gene)
GPS2 Gene - GeneCards | GPS2 Protein | GPS2 Antibody
GPS2 (G Protein Pathway Suppressor 2) is a Protein Coding gene. Diseases associated with GPS2 include Liposarcoma and Hepatitis C Virus . Among its related pathways are Chromatin o…
GeneCards
https://www.genecards.org/cgi-bin/carddisp.pl?gene=GPS2
Wikipedia
GeneCards
Wikipedia
https://en.wikipedia.org/wiki/GPS2_(gene)
GPS2 (gene) - Wikipedia
G protein pathway suppressor 2 is a protein that in humans is encoded by the GPS2 gene. This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) si…
GeneCards
https://www.genecards.org/cgi-bin/carddisp.pl?gene=GPS2
GPS2 Gene - GeneCards | GPS2 Protein | GPS2 Antibody
GPS2 (G Protein Pathway Suppressor 2) is a Protein Coding gene. Diseases associated with GPS2 include Liposarcoma and Hepatitis C Virus . Among its related pathways are Chromatin o…

Wikipedia
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GPS2 (gene) - Wikipedia
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GeneCards
https://www.genecards.org › cgi-bin › carddisp.pl
GPS2 Gene - GeneCards | GPS2 Protein | GPS2 Antibody
Mar 30, 2025 · GPS2 (G Protein Pathway Suppressor 2) is a Protein Coding gene. Diseases associated with GPS2 include Liposarcoma and Hepatitis C Virus. Among its related pathways are Transcriptional Regulation by MECP2 …
National Center for Biotechnology Information
https://www.ncbi.nlm.nih.gov › gene
2874 - Gene ResultGPS2 G protein pathway suppressor 2 [ (human)]
G protein pathway suppressor 2 (GPS2) is a transcriptional corepressor important for estrogen receptor alpha-mediated transcriptional regulation.
nih.gov
https://pmc.ncbi.nlm.nih.gov › articles
Loss of G-Protein Pathway Suppressor 2 Promotes Tumor Growth …
GPS2 has recently been identified as a significantly mutated gene in breast cancer and other malignancies and proposed to work as a putative tumor suppressor. However, molecular …
RDDC
https://rddc.tsinghua-gd.org › gene
GPS2 gene | GPS2 gene mutation Pathogenicity | Target- RDDC
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently …
National Center for Biotechnology Information
https://www.ncbi.nlm.nih.gov › gtr › genes
GPS2 G protein pathway suppressor 2 - NIH Genetic Testing …
Jun 17, 2024 · This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could …
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What is G protein pathway suppressor 2?
G protein pathway suppressor 2 is a protein that in humans is encoded by the GPS2 gene. This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades.
GPS2 (gene) - Wikipedia
en.wikipedia.org
What diseases are associated with GPS2?
Diseases associated with GPS2 include Liposarcoma and Hepatitis C Virus. Among its related pathways are Transcriptional Regulation by MECP2 and Gene expression (Transcription). Gene Ontology (GO) annotations related to this gene include transcription corepressor activity and GTPase inhibitor activity.
GPS2 Gene - GeneCards | GPS2 Protein | GPS2 Antibody
genecards.org
What is GPSM2 gene ontology?
Among its related pathways are GPCR downstream signalling and Signal Transduction. Gene Ontology (GO) annotations related to this gene include GTPase regulator activity and GDP-dissociation inhibitor activity. An important paralog of this gene is GPSM2.
GPSM1 Gene - GeneCards | GPSM1 Protein | GPSM1 Antibody
genecards.org
What is G protein suppressor 2?
G Protein Suppressor 2 (GPS2) is a multifunctional protein that exerts important roles in inflammation and metabolism in adipose, liver, and immune cells. GPS2 has recently been identified as a significantly mutated gene in breast cancer and other malignancies and proposed to work as a putative tumo …
Loss of G-Protein Pathway Suppressor 2 Promotes Tumor Growth ... - Pu…
pubmed.ncbi.nlm.nih.gov
How does G protein pathway suppressor 2 suppress gastric cancer?
G protein pathway suppressor 2 suppresses gastric cancer by destabilizing epidermal growth factor receptor. Loss of G protein pathway suppressor 2 in human adipocytes triggers lipid remodeling by upregulating ATP binding cassette subfamily G member 1. GPS2 promotes erythroid differentiation by control of the stability of EKLF protein.
GPS2 G protein pathway suppressor 2 [ (human)] - National Center for
ncbi.nlm.nih.gov
How does GPS2 promote erythroid differentiation in K562 erythroleukemia cells?
GPS2 promotes erythroid differentiation in K562 erythroleukemia cells primarily via NCOR1. G protein pathway suppressor 2 suppresses gastric cancer by destabilizing epidermal growth factor receptor. Loss of G protein pathway suppressor 2 in human adipocytes triggers lipid remodeling by upregulating ATP binding cassette subfamily G member 1.
GPS2 G protein pathway suppressor 2 [ (human)] - National Center for
ncbi.nlm.nih.gov
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GPS2 Gene: Function, Expression, Research & Clinical Significance
GPS2 is a key regulator of inflammation, lipid metabolism, and mitochondrial homeostasis. It acts by inhibiting the activity of the ubiquitin-conjugating enzyme UBE2N/Ubc13, thereby …
WikiGenes
https://www.wikigenes.org › gene
WikiGenes - GPS2 - G protein pathway suppressor 2
We isolated a novel human cell factor, G-protein pathway suppressor 2 (GPS2), by its ability to bind the HTLV-I oncoprotein, and we show that this factor can potently suppress Tax …
Ensembl Genome Browser
https://grch37.ensembl.org › Homo_sapiens › Gene › Summary
Gene: GPS2 (ENSG00000132522) - Summary - Homo_sapiens
A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt.
nih.gov
https://www.ncbi.nlm.nih.gov › gene
GPS2 G protein pathway suppressor 2 [Homo sapiens (human)] - Gene …
This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently …
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