Feb 25, 2025 · A gastrointestinal stromal tumor, also called a GIST, is a type of cancer that begins in the digestive system. GISTs happen most often in the stomach and small intestine.

Gastrointestinal stromal tumors (GISTs) are the most common malignant subepithelial lesions (SELs) of the gastrointestinal tract. They originate from the interstitial cells of Cajal located within the muscle layer and are characterized by over-expression of the tyrosine kinase receptor KIT.

Apr 11, 2023 · Most GISTs harbor characteristic mutations in KIT or platelet-derived growth factor receptor alpha (PDGFRA), while mutations in succinate dehydrogenase (SDH) or other genes are less frequent. The clinical presentation, diagnosis, and prognosis of GISTs will be discussed here.

Although gastrointestinal stromal tumors (GISTs) are a rare type of cancer, they are the commonest sarcoma in the gastrointestinal tract. Molecularly targeted therapy, such as imatinib therapy, has revolutionized the treatment of advanced GIST and …

The difficulty in assessing the malignant potential and prognoses of GISTs as well as the increasing incidence of “incidental GISTs” presents challenges to gastroenterologists. Recently, endoscopic enucleation has been actively performed as both a diagnostic and therapeutic intervention for GISTs.

A GIST (pronounced “jist”) is an uncommon type of cancer that starts in the digestive tract, also known as the gastrointestinal (GI) tract. This is the path inside our body that food passes through.

Jul 17, 2024 · A gastrointestinal stromal tumor, also called a GIST, is a type of sarcoma that develops in the connective tissue of the gastrointestinal tract. Sarcoma medical oncologist Neeta Somaiah, M.D., shares how this cancer develops, how it’s treated and if it’s curable.

A gastrointestinal stromal tumor (GIST) is a relatively rare type of cancer that most commonly develops in the stomach. However, these tumors can occur anywhere along the digestive tract — from the esophagus (swallowing tube) to the stomach, small intestine, colon and rectum.

Gastrointestinal stromal tumors are tumors of the gastrointestinal tract derived from mesenchymal precursor cells in the gut wall (interstitial cells of Cajal). Diagnosis is usually by endoscopy. Treatment is surgical removal.

Gastrointestinal stromal tumours (GISTs) are rare cancers that develop in the digestive system. They are a type of soft tissue sarcoma. GISTs are most common in people aged 60 to 65 and are rare in people under the age of 40. Most GISTs start in the stomach or small bowel.