Homeobox protein MSX-1, is a protein that in humans is encoded by the MSX1 gene. [5][6] MSX1 transcripts are not only found in thyrotrope-derived TSH cells, but also in the TtT97 thyrotropic tumor, which is a well differentiated hyperplastic tissue that produces both TSHß- and a-subunits and is responsive to thyroid hormone.

The MSX1 gene provides instructions for making a protein that regulates the activity of other genes. The MSX1 gene is part of a larger family of homeobox genes, which control the formation of many body structures during early development.

Mar 30, 2025 · MSX1 (Msh Homeobox 1) is a Protein Coding gene. Diseases associated with MSX1 include Witkop Syndrome and Tooth Agenesis, Selective, 1. Among its related pathways are Gastrulation and Nervous system development. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and p53 binding.

Jul 6, 2016 · In humans, MSX1 variants have been related to tooth agenesis, orofacial clefting, and nail dysplasia. We correlate all MSX1 disease causing variants to phenotypic features to shed light on this...

Feb 8, 2025 · Title: Characterization of novel MSX1 variants causally associated with non-syndromic oligodontia in Chinese families. MSX1 involved selective tooth agenesis and abnormal labial frenum, pedigree, and retrospective study.

Dec 1, 2003 · Vertebrate Msx genes are unlinked, homeobox-containing genes that bear homology to the Drosophila muscle segment homeobox gene. These genes are expressed at multiple sites of tissue-tissue...

Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus. Characterization of novel MSX1 variants causally associated with non-syndromic oligodontia in Chinese families. MSX1 involved selective tooth agenesis and abnormal labial frenum, pedigree, and retrospective study.

Dec 10, 2024 · MSX1 msh homeobox 1 Gene ID: 4487, updated on 10-Dec-2024 Gene type: protein coding Also known as: HOX7; HYD1; ECTD3; STHAG1. See all available tests in GTR for this gene; Go to complete Gene record for MSX1; Go to Variation Viewer for MSX1 variants; Summary. This gene encodes a member of the muscle segment homeobox gene family.

Gene/transcipt that contains an open reading frame (ORF). Protein coding. A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt.

In humans, MSX1 variants have been related to tooth agenesis, orofacial clefting, and nail dysplasia. We correlate all MSX1 disease causing variants to phenotypic features to shed light on this hitherto unclear association. MSX1 truncations cause more …