Gels are semisolid, homogeneous systems with continuous or discrete therapeutic molecules in a suitable lipophilic or hydrophilic three-dimensional network base. Innovative gel systems possess multipurpose applications in cosmetics, food, pharmaceuticals, biotechnology, and so forth.

Topical gels are a topical drug delivery dosage form commonly used in cosmetics and treatments for skin diseases because of their advantages over cream and ointment. [1][2][3][4] They are formed from a mixture of gelator, solvent, active drug, and other excipients, and can be classified into organogels and hydrogels. [1][5][6][7] Drug formulatio...

Jul 1, 2013 · A gel is a solid or semisolid system of at least two constituents, consisting of a condensed mass enclosing and interpenetrated by a liquid. Delivery of drugs to the skin is an effective and targeted therapy for local dermatological disorders.

Mar 1, 2021 · Over the past decade gel-based systems have emerged as a new approach to drug delivery system, attracting the interest of the scientific community. In-situ gels are a type of hydrogel which...

Jun 1, 2023 · A gel is a cross linked polymer network that has swollen in a liquid medium. Its properties are heavily influenced by the interaction of the solid-state polymer and the liquid component.

Oct 1, 2015 · Many drugs can be dissolved in the gels and possibly given via and into the skin because the surfactants enhance skin penetration. The potential of these cyclosporine-containing amphiphilic...

In diabetes management, long-acting gels are crucial for the continuous and controlled delivery of medications to effectively regulate blood glucose levels, reflecting a trend towards enhancing patient convenience and treatment success [11, 12, 13, 14, 15, 16, 17].

Jan 1, 2017 · Novel gels prepared by nanotechnology, including vesicular gels, nanogels, emulgels, and so forth, have established their efficacy in terms of drug loading and controlled release of drug from different routes of administration. These novel gels have proven their effectiveness as smart gel systems for drug delivery and other emerging fields.

Apr 10, 2022 · Gels are transparent or translucent, non-greasy, semisolid systems preparation consisting of dispersions of small or large molecules in an aqueous liquid vehicle, which has been thickened with a gelling agent. Gels can be a single phase or a biphasic system.

Small molecular-based gel systems, constructed by inactive compounds or active pharmaceutical ingredients, have been extensively studied as carriers for drug delivery in pharmaceutical field, such as oral formulations, injectable formulations, and transdermal formulations.