GSK-3 activity promotes conditional association of CREB and its co-activators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis, which are compromised following GSK …

Apr 6, 2016 · For the first time, we demonstrated that GSK-3α is regulated by CREB in lung cancer and is required for the cell viability. These findings implicate CREB-GSK-3α axis as a …

Nov 27, 2021 · Glycogen synthase kinase-3 (GSK3) may be the busiest kinase in most cells, with over 100 known substrates to deal with. How does GSK3 maintain control to selectively …

Mar 3, 2007 · Our results extend the role of GSK-3/CREB signaling to the more general paradigm of gene regulation downstream of growth factor receptors. GSK-3 is active under conditions of …

Jun 15, 2010 · We demonstrate here that GSK-3 maintains the MLL leukemia stem cell transcriptional program by promoting the conditional association of CREB and its coactivators …

We propose that phosphorylation by GSK-3 at the P-motif promotes CREB-H ER retention and suppresses its transport and processing and present a model for dual integrated control, …

Apr 6, 2016 · For the first time, we demonstrated that GSK-3α is regulated by CREB in lung cancer and is required for the cell viability. These findings implicate CREB-GSK-3α axis as a …

Apr 6, 2016 · For the first time, we demonstrated that GSK-3α is regulated by CREB in lung cancer and is required for the cell viability. These findings implicate CREB-GSK-3α axis as a …

Dec 1, 2023 · Glycogen synthase kinase 3 (GSK-3) is a highly conserved protein serine/threonine kinase that plays a central role in a wide variety of cellular processes to coordinate catabolic …

Jun 6, 2010 · GSK-3 activity promotes conditional association of CREB and its co-activators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis, which are compromised …