Granulomatosis with Polyangiitis can cause many kinds of skin rashes. The most common rash occurs in the form of small purple or red dots on the lower extremities (known as “palpable purpura”).

What is granulomatosis with polyangiitis? Granulomatosis with polyangiitis is an uncommon but potentially fatal form of vasculitis. There is an immune reaction in which antibodies damage small blood vessel walls and surrounding tissues. Multiple organs are often involved.

Nov 2, 2024 · Granulomatosis with polyangiitis (GPA) is the new name for what used to be called Wegener’s granulomatosis. It’s an autoimmune disease that can affect your whole body, but especially affects your lungs and kidneys. Polyangiitis …

Skin involvement in granulomatosis with polyangiitis (GPA) is common and can appear as an initial presentation of the disease or more commonly through its course. We report a case of a 24-year-old male patient, previously diagnosed as having GPA, ...

Jan 14, 2025 · Granulomatosis with polyangiitis (GPA) is a rare disease that causes swelling, also called inflammation, of small blood vessels. This condition mainly affects blood vessels in the nose, sinuses, throat, lungs and kidneys. But it can affect any organ. GPA used to be called Wegener granulomatosis.

Cutaneous manifestations of granulomatosis with polyangiitis may facilitate early disease diagnosis. Likewise, a manifestation such as palpable purpura may be a predictor of kidney damage. Key words: granulomatosis with polyangiitis, skin, vascular purpura.

Depending on which systems are involved, additional symptoms can include skin rashes, inner ear pain, swollen and painful joints, and numbness or tingling in the limbs. GPA is most common in middle-aged adults, although it can occur at any age.

GPA can cause a variety of symptoms depending on which organs are affected. Possible symptoms include: • Sinus congestion & sinusitis. • Fevers, weight loss & unusually severe fatigue Many of the above symptoms can also be seen in infections, chronic lung diseases and cancers.

Skin Rashes. Skin rashes affect 40–50% of GPA patients and result from inflammation of small blood vessels in the skin. These rashes often appear as red or purple spots, known as purpura, on the legs, arms, or trunk. They may be painful or itchy, and in some cases, GPA can cause ulcers or sores.

GPA is characterised by inflammation of the small blood vessels including the capillaries. Who are affected? It is most common in middle aged and elderly people but can affect young adults and children.