The genO-GFP rat is suitable for organ & tissue transplantations and used in many biomedical fields (development, toxicology, orthotopic transplantation). The genO-GFP rat line has been developed by inserting, within the rat Rosa26 locus, a …

We generated transgenic rats that express exogenous fluorescent proteins such as eGFP and mRFP1.

The goal of this study is to establish a Cre/loxP rat resource for conditional and physiologically predictive rat models of human diseases. The laboratory rat (R. norvegicus) is a central experimental animal in several fields of biomedical research, ...

Aug 31, 2001 · The purpose of this study is to evaluate green fluorescent protein (GFP) transgenic rats for use as a tool for organ transplantation research. The GFP gene construct was designed to express ubiquitously.

Certain hematopoietic cell types display distinct expression levels of GFP, allowing identification of different cells types by FACS analysis. This strain is a useful tool for studying hematopoietic cell differentiation and in vivo leukocyte tracking.

The constitutively expressing GFP transgenic strains showed tissue-specific differences in GFP expression, and GFP immunohistochemistry amplified the fluorescent signal.

Sep 16, 2019 · Here, we describe the generation and characterization of a new transgenic rat strain in which conditional expression of the ZsGreen fluorescent protein gene requires the presence of exogenous Cre...

Dec 2, 2014 · With its high levels of GFP, hTH-GFP rat reporter line 12141 allows for anatomical visualization of the rat SNpc and/or VTA and detailed analysis of midbrain DA neurons and axonal projections after toxin treatment in vivo.

Jan 1, 2012 · We have further extended the techniques of genetic engineering to rats, rabbits, and pigs, and have created corresponding GFP-transgenic animals. The GFP-positive organs of these animals provide valuable sensors in preclinical settings for …

Aug 19, 2016 · To elucidate the intercellular transfer fate of EVs in vivo, we generated a new transgenic (Tg) rat model using green fluorescent protein (GFP)-tagged human CD63. CD63 protein is highly...