Immunohistochemical staining for glial fibrillary acidic protein (GFAP) is standard for visualization of reactive astrocytes in tissue sections, whereas various forms of astrocytic damage remain to be described in detail.

GFAP is a superior marker to S-100 and vimentin as observed by few authors based on immunostaining pattern of GFAP, vimentin, and S-100 using IHC techniques in human glial tumors.

Feb 1, 2024 · Immunohistochemical upregulation of glial fibrillary acidic protein (GFAP) is commonly used to detect astrogliosis in tissue sections and includes measurement of intensity and/or distribution of staining.

Jul 2, 2021 · Cite this page: Pernick N. Glial fibrillary acidic protein (GFAP). PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/stainsgfap.html. Accessed ...

Glial fibrillary acidic protein (GFAP) is an intermediate filament protein of 52kD reported to be expressed in glial cells, for example, astrocytes and ependymal cells.

Classification of glial tumors. For the initial technical component only immunohistochemical (IHC) stain performed, the appropriate bill-only test ID will be reflexed and charged (IHTOI). For each additional technical component only IHC stain performed, an additional bill-only test ID will be reflexed and charged (IHTOA). Immunohistochemistry (IHC)

May 4, 2005 · In the peripheral nervous system enteric Schwann cells and satellite cells of human sensory ganglia express GFAP. Outside the nervous system, GFAP is seen in myoepithelial cells and chondroblasts, in the former coexpressed with …

May 3, 1996 · Glial fibrillary acidic protein (GFAP) is the principal marker for brain astrocytes. The present study aims to examine the variability in GFAP immunohistochemistry in formalin-fixed human brain.

Compared to the classic PAP procedures, avidin-biotin techniques are particularly valuable as background staining is virtually eliminated while the specific reaction is amplified.3,4 Glial fibrillary acidic protein (GFAP) is a 51,000 molecular weight intermediate filament protein expressed in normal, reactive and neoplastic cells (astrocytes ...

Glial fibrillary acidic protein (GFAP) is an intermediate filament protein of 52 kDa found in glial cells, astrocytes, and ependymal cells. Immunoperoxidase staining for GFAP produces intense cytoplasmic staining of astrocytes, glial cells, and ependymal cells in normal brain.