The murine local lymph node assay (LLNA) is an in vivo test for skin sensitisation. LLNA has largely superseded the guinea pig maximisation test and the Buehler test. It is considered …

Explore LLNA Definitions: Discover the complete range of meanings for LLNA, beyond just its connections to Medical. Contribute an Abbreviation: Have an abbreviation we haven't listed? …

The local lymph node assay (LLN A) relies on the detection of increase DNA synthesis via tritiated thymidine incorporation. Sensitization is measured as a function of lymph node cell …

The murine local lymph node assay (LLNA) is a test method developed to assess whether a chemical has the potential to induce allergic contact dermatitis (ACD) in humans.

The LLNA provides a quantitative endpoint, dose-responsive data, allows for prediction of potency (EC3; effective concentration for a SI of 3 in proliferation of lymph node cells) and does not …

Find out what is the full meaning of LLNA on Abbreviations.com! 'Local Lymph Node Assay' is one option -- get in to view more @ The Web's largest and most authoritative acronyms and …

Mar 13, 2025 · One of the LLNA modifications evaluated by NICEATM and ICCVAM in response to the CPSC nomination was the reduced LLNA (rLLNA). When used to test a substance for …

Feb 12, 2003 · The local lymph node assay (LLNA) was developed originally as a method for the identification of chemicals that have the potential to cause skin sensitization and allergic …

The local lymph node assay (LLNA) is a murine model developed to evaluate the skin sensitization potential of chemicals. The LLNA is an alternative approach to traditional guinea …

Sep 4, 2024 · The reduced LLNA test method can be used in situations where dose-response information is not required. For example, it can be used for a 1 dose level (limit dose). Test …