Friend leukemia integration 1 transcription factor (FLI1), also known as transcription factor ERGB, is a protein that in humans is encoded by the FLI1 gene, which is a proto-oncogene. [5] [6] [7]

Dec 25, 2024 · FLI1 (Fli-1 Proto-Oncogene, ETS Transcription Factor) is a Protein Coding gene. Diseases associated with FLI1 include Bleeding Disorder, Platelet-Type, 21 and Isolated Delta …

Mar 4, 2021 · We developed an in vivo T cell CRISPR screening platform and identified a key mechanism restraining T EFF biology through the ETS family TF, Fli1. Genetic deletion of Fli1 …

Feb 25, 2021 · An in vivo T cell CRISPR screening platform identifies Fli1 as a factor modulating CD8+ T cell effector differentiation with limited effects on memory or exhaustion.

FLI1 regulates radiotherapy resistance in nasopharyngeal carcinoma through TIE1-mediated PI3K/AKT signaling pathway. FLI1 and FRA1 transcription factors drive the transcriptional …

Feb 28, 2022 · Keywords: Cancer; ETS family; Erythropoiesis; FLI1; Hematopoiesis; Leukemia; Megakaryopoiesis.

Emerging evidence has shown that Fli1 is implicated in the etiology of several autoimmune diseases, including systemic sclerosis (SSc) and systemic lupus erythematosus (SLE). In this …

Being initially described as a factor of virally-induced leukemias, Fli1 (Friend leukemia integration 1) has attracted considerable interest lately due to its role in both healthy physiology and a …

Jan 4, 2025 · Title: FLI1 is associated with regulation of DNA methylation and megakaryocytic differentiation in FPDMM caused by a RUNX1 transactivation domain mutation. An intricate …

The FLI1 gene provides instructions for making the FLI protein, which controls the activity (transcription) of genes. Learn about this gene and related health conditions.