If limited AML FISH probes are preferred, order AMLMF / Acute Myeloid Leukemia (AML), Specified FISH, Varies and request specific probes for targeted abnormalities. This test is intended for instances when the entire AML fluorescence in situ hybridization (FISH) panel is needed for an adult patient.

Mar 4, 2025 · Reflex results will be reported separately as AML Standard Reflex Panel. Disease(s): Acute myeloid leukemia Note: STAT processing is available by request for PML-RARA.

• Acute myeloid leukemia (AML) is a clinically, morphologically and genetically heterogeneous disease that results in clonal expansion of myeloid blasts in the peripheral blood, bone marrow, or other tissue . • A general AML workup at the time of diagnosis consists of drawing a …

Mar 31, 2025 · This test is a diagnostic and prognostic test for acute myeloid leukemia; detection rate is 80% of the known chromosome causes of AML. Special Instructions Indicate pertinent clinical diagnosis and previous cytogenetic studies on the test request form.

Fluorescence In-Situ Hybridization (FISH) is a molecular cytogenetic technique used in the identification of microdeletions, aneuploidies, marker chromosomes, and translocations on either metaphase cells or interphase nuclei from patient samples with acquired abnormalities (e.g. hematologic disorders).

This FISH panel is designed to detect the most common, and/or prognostically-significant abnormalities in AML with recurrent genetic abnormalities and in therapy-related AML (Swerdlow et al. 2008). Recurrent abnormalities are observed in the majority of AML cases.

This test is intended for instances when limited acute myeloid leukemia (AML) fluorescence in situ hybridization (FISH) probes are needed based on specific abnormalities or abnormalities identified in the diagnostic sample.

Aug 21, 2023 · Use to identify cytogenetic abnormalities with diagnostic and prognostic significance in suspected or newly diagnosed acute myeloid leukemia (AML). To monitor therapeutic response using specific probes, refer to Chromosome FISH, Interphase ( 2002298 ).

FISH continues to be a powerful technique in the diagnosis of AML, with higher resolution than conventional cytogenetic analysis, rapid turnaround time, and a considerable diagnostic and prognostic utility.

Jul 22, 2020 · acute myeloid leukemia (AML) for diagnostic and prognostic purposes as well as for follow-up to evaluate patient response to therapy. Synonyms: FISH, Hematopoietic malignancy, Acute Myeloid Leukemia, AML