Mar 30, 2025 · F2R (Coagulation Factor II Thrombin Receptor) is a Protein Coding gene. Diseases associated with F2R include Thrombosis and Blood Platelet Disease. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and GPCR downstream signalling.

Proteinase-activated receptor 1 (PAR1) also known as protease-activated receptor 1, coagulation factor II receptor and thrombin receptor is a protein that in humans is encoded by the F2R gene. [5]

Variants in the coagulation factor 2 receptor (F2R) gene influence the risk of myocardial infarction in men through an interaction with interleukin 6 serum levels.

There are four mammalian members of the protease-activated receptor (PAR) family: PAR1 – encoded by the gene F2R, PAR2 – F2RL1, PAR3 – F2RL2 and PAR4 – F2RL3, each of these genes has its locus on chromosome 5 except that of PAR4, which is on chromosome 19.

Aug 27, 2024 · Gene target information for F2R - coagulation factor II thrombin receptor (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Protease activated receptor 2 (PAR2) also known as coagulation factor II (thrombin) receptor-like 1 (F2RL1) or G-protein coupled receptor 11 (GPR11) is a protein that in humans is encoded by the F2RL1 gene.

Dec 17, 2023 · Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Jan 30, 2024 · Coagulation factor 2 thrombin receptor (F2R), a member of the G protein-coupled receptor family, plays an important role in regulating blood clotting through protein hydrolytic cleavage mediated receptor activation.

Sep 14, 2016 · Gene target information for F2R - coagulation factor II thrombin receptor (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

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