Jul 22, 2021 · Enhancer of zeste homolog 2 (EZH2) is abnormally highly expressed in pancreatic cancer (PC). However, it is not ideal to treat PC by inhibiting EZH2. This study reported that …

The relationship between peroxisome proliferator-activated receptor γ (PPARG) expression and epigenetic changes occurring in colorectal-cancer pathogenesis is largely unknown. We …

Sep 20, 2016 · By using transcriptomic and epigenomic analysis, we found that stable repression of a small group of genes by IFN-γ is associated with recruitment of the histone …

Sep 28, 2016 · EZH2, collagen 1a1 (Col1a1), α-smooth muscle actin (ACTA2), fos-related antigen 2 (Fra2), and peroxisome proliferator-activated receptor gamma (PPARG) expression were …

The relationship between peroxisome proliferator-activated receptor γ (PPARG) expression and epigenetic changes occurring in colorectal-cancer pathogenesis is largely unknown.

The variants were limited to five known genes: epigenetic regulators (EZH2, SIRT1) and pan-peroxisome proliferator-activated receptors (PPARA, PPARD, PPARG). Results: The class …

Collectively, these results demonstrate that PPARg is one of the major target genes of EZH2 during neuron differentiation of hMSCs and that its expression is suppressed at the MSC …

In animal model, rats implanted with intracerebral EZH2-knocked-down hMSCs or hMSCs plus treatment with PPARg agonist (rosiglitazone) showed better improvement than those without …

Feb 6, 2023 · Lar WISP2 on Pparg and Fabp4 activation following addition of BMP4 to NIH3T3 cells exactly where endogenous Wisp2 was silenced with siRNA. We previously showed that …

In HCT116, ZAC is highly recruited at the PPARG promoter after epigenetic treatments correlating with PPARG transcription recovery * P <0.05; ** P = 0.004; *** P = 0.0001. ( C) qChIP analysis …