In an extracted-ion chromatogram (EIC or XIC), also called a reconstructed-ion chromatogram (RIC), one or more m/z values representing one or more analytes of interest are recovered ('extracted') from the entire data set for a chromatographic run. [3]

This mini-review provides a general understanding of electrospray ionisation mass spectrometry (ESI-MS) which has become an increasingly important technique in the clinical laboratory for structural study or quantitative measurement of metabolites in a complex biological sample.

Dec 13, 2023 · 提取离子色谱图（EIC或XIC） 英文全称为：Extracted Ion Chromatogram。它指的是特定质荷比下的色谱图，即m/z固定，横坐标为保留时间，纵坐标为强度。图1中每一种颜色的图就表示一个EIC (XIC) 图。

Optimal ESI + -MS in the selected ion mode (SIM) and full scan (m/z 200-650) modes, as well as ESI + -MS-MS in the multiple reaction monitoring mode (MRM) mode, were assessed and compared...

The achievable sensitivity of electrospray ionization mass spectrometry (ESI-MS) is largely determined by the ionization efficiency in the ESI source and ion transmission efficiency through the ESI-MS interface.

Electrospray ionization (ESI) is a technique used in mass spectrometry to produce ions using an electrospray in which a high voltage is applied to a liquid to create an aerosol. It is especially useful in producing ions from macromolecules because it overcomes the propensity of these molecules to fragment when ionized.

Feb 8, 2005 · Selected ion current or extracted ion chromatogram (EIC or XIC) shows the signal from a single mass selected by the user, whether or not that mass is the most intense at any given time. The BPC will often look similar to the TIC, but less noisy.

Oct 21, 2014 · Extracted ion chromatogram (EIC) extraction and chromatographic peak detection are two important processing procedures in liquid chromatography/mass spectrometry (LC/MS)-based metabolomics data analysis. Most commonly, the LC/MS technique employs electrospray ionization as the ionization method.

Tandem Mass Spectrometry (MS/MS or MSn) • Soft ionization techniques such as ESI only result in parent ions, revealing no structural information • Hard ionization techniques yield fragments, but specific precursor-product relationships cannot be obtained • Isolate and fragment precursor ion and measure m/z of product ions to obtain

IC-MS is a robust, sensitive, and selective technique used for the determination of polar contaminants like inorganic anions, organic acids, haloacetic acids, oxyhalides, or alkali and alka-line earth metals.