Mar 30, 2025 · NCBI Gene Summary for MAPK1 Gene This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation ...

Mar 30, 2025 · The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals.

Mar 30, 2025 · NCBI Gene Summary for MAPK3 Gene The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of ...

Showing of 8,385 Results for ERK Search Time: 0 ms. Export Show: Symbol Description Category UniProt ID GIFtS GC id Score; 1: MAPK1: Mitogen-Activated Protein Kinase 1: Protein Coding: P28482: 65: GC22M021759: 47.26: 2: MAPK3: Mitogen-Activated Protein Kinase 3: Protein Coding ... Gene symbols for ERK.

Mar 30, 2018 · EPHB2 (EPH Receptor B2) is a Protein Coding gene. Diseases associated with EPHB2 include Bleeding Disorder, Platelet-Type, 22 and Prostate Cancer/Brain Cancer Susceptibility. Among its related pathways are GPCR Pathway and EPH-Ephrin signaling.

Mar 30, 2025 · As part of the MAPK/ERK signaling pathway, acts as a negative regulator of apoptosis in cardiomyocytes via interaction with STUB1/CHIP and promotion of STUB1-mediated ubiquitination and degradation of ICER-type isoforms of CREM (By similarity). May have a role in muscle cell differentiation.

Mar 30, 2025 · EIF2AK3 (Eukaryotic Translation Initiation Factor 2 Alpha Kinase 3) is a Protein Coding gene. Diseases associated with EIF2AK3 include Epiphyseal Dysplasia, Multiple, With Early-Onset Diabetes Mellitus and Menkes Disease. Among its related pathways are Signaling by ALK in cancer and Alzheimer's disease and miRNA effects.

Mar 30, 2025 · The PP2A-PPP2R5C holoenzyme may specifically dephosphorylate and activate TP53 and play a role in DNA damage-induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation. ( 2A5G_HUMAN,Q13362)

Gene overlap in member pathways for MAPK-Erk Pathway SuperPath Associated Genes for MAPK-Erk Pathway Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

Mar 30, 2025 · Among its related pathways are PAK Pathway and Signal transduction_Erk Interactions- Inhibition of Erk. Gene Ontology (GO) annotations related to this gene include protein kinase binding and protein tyrosine phosphatase activity. An …