Epsins are a family of highly conserved membrane proteins that are important in creating membrane curvature. Epsins contribute to membrane deformations like endocytosis, and block …

Epsin is a multifaceted protein that apart from its classical role in cargo recognition and endocytic network stabilization, plays a crucial role in signaling. Epsin is required for the activation of the …

Epsins are a family of adaptor proteins involved in clathrin-dependent endocytosis. In the vasculature, epsins 1 and 2 are functionally redundant members of this family that are …

Besides inducing membrane curvature, epsin also plays a key function as adaptor protein, coupling various components of the clathrin-assisted uptake and fulfils an important role in …

Nov 26, 1999 · Epsin (epsin 1) is an interacting partner for the EH domain-containing region of Eps15 and has been implicated in conjunction with Eps15 in clathrin-mediated endocytosis. …

Aug 20, 1998 · Here we investigate the function of Eps15 by characterizing an important binding partner for its region containing EH domains 9; this protein, epsin, is closely related to the …

Dec 1, 2002 · Endocytic adaptor proteins select specific cargo for internalization by endocytosis through clathrin-coated pits or vesicles. Recent studies indicate that epsins might also be …

Epsin is a conserved family of endocytic proteins that recognize ubiquitinated membrane receptors, facilitate membrane bending, and aid in the formation of clathrin-coated pits. …

Sep 15, 2020 · Epsins are a family of adaptor proteins involved in clathrin-dependent endocytosis. In the vasculature, epsins 1 and 2 are functionally redundant members of this family that are …

Feb 3, 2013 · Epsins, a small family of clathrin-mediated endocytic adaptor proteins, are reportedly upregulated in a variety of cancers. Importantly, loss of epsins protects against …