
Ephrin receptor - Wikipedia
Eph receptors (Ephs, after erythropoietin-producing human hepatocellular receptors) are a group of receptors that are activated in response to binding with Eph receptor-interacting proteins …
Eph Receptors and Ephrins: Therapeutic Opportunities - PMC
Eph receptors bind ephrins on neighboring cells, generating cell contact-dependent bidirectional signals that regulate cell shape, movement, survival and proliferation (1; 3; 4). Eph “forward” …
Emerging Roles for Eph Receptors and Ephrin Ligands in Immunity
Eph receptors are the largest family of receptor tyrosine kinases and mediate a myriad of essential processes in humans from embryonic development to adult tissue homeostasis …
Ephs and ephrins: Current Biology - Cell Press
Feb 6, 2017 · In this Primer we will discuss some of the key aspects of signalling by Ephs and ephrins that make them pivotal players in health and disease. Eph receptors were first …
The Blood-Brain Barrier and the EphR/Ephrin System: Perspectives …
Among regulatory molecules, the erythropoietin-producing-hepatocellular carcinoma receptors (EphR) and their Eph receptor-interacting signals (ephrins) play a pivotal role in EC …
Master regulators of neurogenesis: the dynamic roles of Ephrin ...
Nov 6, 2024 · Here, we review our current understanding of the complex and dynamic role of EphRs in the brain and discuss how deregulation of these receptors contributes to disease, …
Therapeutic targeting of EPH receptors and their ligands
Dec 31, 2013 · Critical roles for EPH receptor (EPH)–ephrin signalling in a range of chronic and regenerative diseases are increasingly being recognized. In particular, the complex roles of …
Ephs and ephrins - PubMed
Feb 6, 2017 · Eph receptors comprise the largest family of receptor tyrosine kinases (RTKs), with fourteen receptors divided into two subfamilies - EphAs and EphBs. Yet, despite their …
Eph Receptor and Ephrin Signaling in Developing and Adult Brain …
Feb 1, 2007 · Here, we report on the characterization of Eph receptor and ephrin orthologs in the honeybee, Apis mellifera (Am), and their role in learning and memory. In situ hybridization for …
Eph/ephrin molecules--a hub for signaling and endocytosis
Nov 15, 2010 · Eph receptor tyrosine kinases and their ephrin ligands are critical regulators of cell contact-dependent signaling and patterning. Eph/ephrin binding can lead to very diverse …