In organic chemistry, enolates are organic anions derived from the deprotonation of carbonyl (RR'C=O) compounds. Rarely isolated, they are widely used as reagents in the synthesis of …

Aug 16, 2022 · Enolates are nucleophiles and have many useful reactions with electrophiles. In this post we will cover the reactions of enolates with H+ , halogens, and simple electrophiles. …

The Ambident Character of Enolate Anions. Since the negative charge of an enolate anion is delocalized over the alpha-carbon and the oxygen, as shown earlier, electrophiles may bond …

Apr 14, 2023 · An enolate is simply a deprotonated enol, which is itself a hydroxyalkene. Enols are in equilibrium with the keto form (preferred), and the enolates themselves have resonance …

Jan 23, 2023 · Some bases that have been used for enolate anion formation are: NaH (sodium hydride, pK a > 45), NaNH 2 (sodium amide, pK a = 34), and LiN[CH(CH 3) 2] 2 (lithium …

Aug 19, 2022 · Many ketones are capable of forming two different enolates, depending on which alpha-carbon is deprotonated. The question is, which one will be favored? Generally enolates …

Enolates, also known as oxyallyl anions, are flexible reagents that may be used to make -substituted carbonyl compounds, making them crucial intermediates in the synthesis of …

Ketones and aldehydes are two very important types of organic compounds. This article will focus on enols and enolates, which are two closely related forms that give ketones and aldehydes …

Apr 8, 2010 · Five factors that influence the relative proportion of keto/enol: 1. Aromaticity. Answer: The more electron-poor the carbonyl, the greater will be its ability to stabilize negative …

Enolate formation is the process by which a deprotonated carbonyl compound (like a ketone or aldehyde) creates an enolate ion, which is a resonance-stabilized intermediate important in …