Enamine, the leading provider of chemical compounds and drug discovery services, and ChemPass, a contract research organization for computational and AI-assisted software, today announced their start of strategic partnership to provide hit discovery solutions to their customers.

To save your time and efforts, we conveniently categorized the entire Enamine's building blocks collection by chemical functional groups: carboxylic acids, primary and secondary amines, boronic compounds, etc. Download latest selections and special subsets as separate SD files.

Over the past 20 years, Enamine has become a global provider of Screening Compounds, Building Blocks, and Fragments for supporting a wide range of research programs conducted by pharmaceutical and biotech companies, drug discovery centres, academic institutions and other research organizations worldwide.

Therefore, Enamine, a global leader in the chemical building block market, has developed a special product - the Fast MADE Building Blocks. This is a special set of Enamine MADE (MAke-on-DEmand) building blocks (BBs) that will be synthesized and delivered to our customers in ultra-short terms.

Diversity Libraries. A complete suite of non-overlapping screening libraries ranging from 5k to 500k compounds. Diverse and carefully selected from lead-like chemotypes to provide new hits even for well-known targets.

Enamine designs, develops and synthesizes chemical reagents, scaffolds and intermediates widely known as building blocks. They are convenient for using in medicinal chemistry and synthesis of combinatorial compound libraries.

Nov 21, 2024 · Enamine, a scientifically driven provider of chemistry and biology services with the world’s largest catalog of building blocks screening compounds, announced today performance results for Enamine Fast MADE building blocks.

Chemical modifications of these anionic residues can further restrict the conformational landscape, strengthen interactions, and reduce metabolic degradation. Enamine offers a collection of anionic amino acids with diverse substituents, including innovative molecules built on cyclic scaffolds.

The library composition was visually checked by Enamine and ICR experts to remove trivial and MedChem unfriendly compounds. The distribution of CAB classes took into account both medicinal chemistry attractiveness and synthetic tractability, the latter being crucial for the hit follow-up stage.

Despite its size, the REAL database is easy to work with. Along with SMILES and catalog IDs, you can find for each REAL molecule important physicochemical parameters (MW, SLogP, HBA, HBD, etc.), relation to the REAL database subsets, and type of chemistry and, therefore, an effort, utilized for the synthesis (“s”, simple chemistry, standard effort, “m”, advanced chemistry, high …