Here we show that eIF4H (eukaryotic translation initiation factor 4H), an activator of the RNA helicase eIF4A, is overexpressed in lung carcinomas and predictive of response to …

Eukaryotic translation initiation factor 4H is a protein that in humans is encoded by the EIF4H gene. [5][6][7] This gene encodes one of the translation initiation factors, which function to …

Mar 28, 2025 · Complete information for EIF4H gene (Protein Coding), Eukaryotic Translation Initiation Factor 4H, including: function, proteins, disorders, pathways, orthologs, and expression.

Results demonstrate that eukaryotic translation initiation factor 4H (eIF4H) plays a crucial role in translational control. Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF …

Feb 6, 2009 · Here we report the topology of the eIF4A/4G/4H helicase complex, which is built from multiple experimentally observed domain-domain contacts. Remarkably, some of the …

Results show that eIF4H can significantly enhance the helicase activity of eIF4AI by strongly binding both to loop structures within the RNA transcript as well as to eIF4AI. In the presence …

Aug 17, 2001 · Eukaryotic initiation factor (eIF) 4A is a DEAD box RNA helicase that works in conjunction with eIF4B, eIF4H, or as a subunit of eIF4F to unwind secondary structure in the 5' …

Mar 5, 2024 · An alternative splicing isoform of eukaryotic initiation factor 4H promotes tumorigenesis in vivo and is a potential therapeutic target for human cancer. Wu D, Matsushita …

Apr 7, 2024 · Results demonstrate that eukaryotic translation initiation factor 4H (eIF4H) plays a crucial role in translational control. Title: Key contribution of eIF4H-mediated translational …

Jan 23, 2007 · Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA. Gene Ontology (GO) annotations organized by slimming set. EIF4H is …