EIF3A Gene - GeneCards | EIF3A Protein | EIF3A Antibody
Mar 28, 2025 · EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A) is a Protein Coding gene. Diseases associated with EIF3A include Craniotubular Dysplasia, Ikegawa Type and …
eIF3: a factor for human health and disease - PMC
The eukaryotic initiation factor 3 (eIF3) is one of the most complex translation initiation factors in mammalian cells, consisting of several subunits (eIF3a to eIF3m). It is crucial in translation …
EIF3A - Wikipedia
Eukaryotic translation initiation factor 3 subunit A (eIF3a) is a protein that in humans is encoded by the EIF3A gene. [5] [6] [7] It is one of the subunits of Eukaryotic initiation factor 3 (eIF3) a …
eIF3a regulation of mTOR signaling and translational control via …
eIF3a (eukaryotic translation initiation factor 3a), a subunit of the eIF3 complex, has been suggested to play a regulatory role in protein synthesis and in cellular response to DNA …
eIF3a: A new anticancer drug target in the eIF family - PubMed
Jan 1, 2018 · eIF3a is the largest subunit of eIF3, which is a key player in all steps of translation initiation. During the past years, eIF3a is recognized as a proto-oncogene, which is an …
eIF3a function in immunity and protection against severe sepsis …
Mar 1, 2025 · In this study, we investigated the in vivo function of eIF3a using eIF3a knockout and knockdown mouse models and found that eIF3a deficiency resulted in splenic tissue structural …
EIF3A eukaryotic translation initiation factor 3 subunit A [ (human)]
Translation initiation factor eIF3a regulates glucose metabolism and cell proliferation via promoting small GTPase Rheb synthesis and AMPK activation. YTHDF3 Facilitates eIF2AK2 …
Eukaryotic initiation factor 3 - Wikipedia
In humans, eIF3 consists of 13 nonidentical subunits (eIF3a-m) with a combined molecular weight of ~800 kDa, making it the largest translation initiation factor. [3] The eIF3 complex is broadly …
Systematic analyses of the role of prognostic and immunological EIF3A ...
Eukaryotic initiation factor 3a (EIF3A), a “reader” protein for RNA methylation, has been found to be involved in promoting tumorigenesis in a variety of cancers. The impact of EIF3A in clear …
eIF3a is the largest subunit of eIF3, which is a key player in all steps of translation initiation. During the past years, eIF3a is recognized as a proto-oncogene, which is an important …
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